{"id":27521,"date":"2016-09-27T11:29:06","date_gmt":"2016-09-27T09:29:06","guid":{"rendered":"https:\/\/www.ioveneto.it\/tumori-ereditari\/"},"modified":"2023-03-16T13:23:10","modified_gmt":"2023-03-16T12:23:10","slug":"hereditary-cancer","status":"publish","type":"page","link":"https:\/\/www.ioveneto.it\/en\/prevention-and-care\/hereditary-cancer\/","title":{"rendered":"Hereditary cancer"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"27521\" class=\"elementor elementor-27521 elementor-4508\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-68c850e8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"68c850e8\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;b386197&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2b6cf50d\" data-id=\"2b6cf50d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7f642721 elementor-widget elementor-widget-heading\" data-id=\"7f642721\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Hereditary cancer<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1be6bfaa elementor-widget elementor-widget-jet-breadcrumbs\" data-id=\"1be6bfaa\" data-element_type=\"widget\" data-widget_type=\"jet-breadcrumbs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-jet-breadcrumbs jet-blocks\">\n\t\t<div class=\"jet-breadcrumbs\">\n\t\t<div class=\"jet-breadcrumbs__content\">\n\t\t<div class=\"jet-breadcrumbs__wrap\"><div class=\"jet-breadcrumbs__item\"><a href=\"https:\/\/www.ioveneto.it\/en\/\" class=\"jet-breadcrumbs__item-link is-home\" rel=\"home\" title=\"Homepage\">Homepage<\/a><\/div>\n\t\t<\/div>\n\t\t<\/div>\n\t\t<\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-198818a4 entry-content elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"198818a4\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;d720a4c&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-188d7d9e\" data-id=\"188d7d9e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-64ad966e elementor-widget elementor-widget-text-editor\" data-id=\"64ad966e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>For each cancer type, between 5 and 10% of cases are attributable to a hereditary form. A tumor is called hereditary when its onset is due to a <a href=\"#geneticmutation\">genetic mutation<\/a>\u00a0transmitted by the parents.<\/p><p>Mutations in parents have a 50% chance of being passed on to their children. The latter <strong>do not inherit the tumor itself, only the predisposition to develop that tumor more easily than the general population<\/strong>.<\/p><p>Individuals carrying a genetic mutation predisposing to a specific cancer are considered to be at high risk and must undergo appropriate prevention protocols.<\/p><p>Identifying and treating tumors with a familial origin is a challenge that requires special resources and skills. This is why IOV created the\u00a0<a href=\"https:\/\/www.ioveneto.it\/en\/unit\/hereditary-tumors-and-oncoendocrinology\/\">Hereditary Tumors Unit<\/a>, which works in synergy with the\u00a0<a href=\"https:\/\/www.ioveneto.it\/en\/unit\/immunology-and-molecular-oncology\/\">Unit of Immunology and Molecular Diagnostics<\/a>,\u00a0specializing in the following neoplasms:<\/p><ul><li>familial colorectal cancer<\/li><li>hereditary endocrine \/ neuroendocrine tumors<\/li><li>hereditary breast and ovary cancer<\/li><li>familial melanoma<\/li><li>hereditary kidney cancer<\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0683813 entry-content elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0683813\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;45d4b65&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2fc923f\" data-id=\"2fc923f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ae33bc5 elementor-widget elementor-widget-spacer\" data-id=\"ae33bc5\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ac1ff0 elementor-widget elementor-widget-text-editor\" data-id=\"3ac1ff0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2>Cancer genetic counseling and genetic testing<\/h2><p>Cancer genetic counseling is available for people with\u00a0<strong>suspected hereditary predisposition<\/strong>\u00a0to develop cancer. Counseling is carried out by a\u00a0<a href=\"https:\/\/www.ioveneto.it\/en\/prevention-and-care\/multidisciplinary-clinics-and-groups-2\/\" rel=\"noopener\">multidisciplinary team<\/a>\u00a0that includes:<\/p><ul><li>a geneticist<\/li><li>an oncologist and \/ or appropriate expert specialist<\/li><li>a psychologist<\/li><\/ul><p>Patients or\u00a0<strong>healthy individuals<\/strong>\u00a0who undergo oncogenetic counseling are invited to provide data on their family, on their illness and that of their relatives. After drawing the family tree and an exhaustive analysis of the medical data, the geneticist verifies the presence or absence of criteria to perform a\u00a0<strong>genetic test<\/strong>.<\/p><p>The choice to undergo a genetic test must be made independently and consciously after receiving, during consultation, all the available information on:<\/p><ul><li>the disease and \/ or the risk of developing it<\/li><li>the genetic investigation and its limits<\/li><li>the risk of illness associated with the test results<\/li><li>the available preventive and \/ or therapeutic possibilities<\/li><\/ul><p>Given the complexity of the topics covered and of the choice to undergo the test and \/ or undertake specific monitoring \/ risk reduction,\u00a0<strong>psychological counseling<\/strong>\u00a0is offered to ensure adequate support and to favor autonomy in decision-making.<br \/>After signing an informed consent form, the patient may decide to undergo the test, which requires a blood sample or a buccal swab. Molecular analysis of genes is performed in the Molecular Biology Laboratory of the Hereditary Tumor and Oncoendocrinology Unit.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ef9516b elementor-widget elementor-widget-text-editor\" data-id=\"ef9516b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Results of the genetic test<\/h3><p>From the genetic test, it is possible to obtain:<\/p><ul><li>an\u00a0<strong>informative<\/strong>\u00a0result (the predisposing mutation is identified);<\/li><li>a\u00a0<strong>non-informative<\/strong>\u00a0result (the predisposing mutation is not identified either because it is on a gene not yet known or because it is not identifiable by the currently available analysis);<\/li><li>a\u00a0<strong>doubtful<\/strong>\u00a0result, if a gene variant of which the pathogenetic effect is not known is identified.<\/li><\/ul><p>The result of the test will be communicated in a subsequent consultation session, in which the molecular data will be interpreted and the most appropriate surveillance program and possible risk reduction options will be illustrated. While awaiting the test result, which may take a relatively long time (even longer than 6 months),\u00a0the patient and family members will be provided with an appropriate surveillance protocol.<\/p><p><strong>Only if the result is informative<\/strong>, can the genetic test be extended to other adult members of the family who wish to do so. In families where a mutation that predisposes to cancer is identified, the family members at risk will be recommended for genetic testing by the patient or family doctor with indications to contact the\u00a0<a href=\"https:\/\/www.ioveneto.it\/en\/unit\/hereditary-tumors-and-oncoendocrinology\/\">Hereditary Tumors Unit<\/a>.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6242822 entry-content elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6242822\" data-element_type=\"section\" id=\"geneticmutation\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;615c458&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b9f8810\" data-id=\"b9f8810\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c15b042 elementor-widget elementor-widget-spacer\" data-id=\"c15b042\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0a5fdcf elementor-widget elementor-widget-text-editor\" data-id=\"0a5fdcf\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2>Genetic mutation<\/h2><p>Cancer is now considered a disease with a genetic component characterized by uncontrolled cell growth. The cells of our body receive control signals that tell them when to grow, when to multiply and when growth must stop. In a tumor, cells do not respond to the control signals, due to alterations of their genetic heritage, and grow and multiply irregularly spreading in different parts of the body. The event that determines the alteration is called\u00a0<strong>mutation<\/strong>. When a gene undergoes a mutation (due to biological, chemical and physical causes), the cell will receive improper information about its function.<\/p><p>Tumors, for the most part, are\u00a0<strong>sporadic<\/strong>: the mutation develops randomly without a particular family predisposition. The mutation originates in the DNA of a small group of cells and determines a genetic error that will perpetuate in the descendants of those cells, which, accumulating in a specific organ, will initially replace the healthy tissue and then spread to nearby or distant organs ( metastases).<\/p><p>While in sporadic tumors, the genetic mutation is present only in the tumor cells, and therefore only in the area of the organ affected by the neoplasia, in the case of\u00a0<strong>hereditary tumors<\/strong>, the mutation is present in all the patient\u2019s cells. To demonstrate that the predisposition to the development of a tumor is hereditary and to be able to identify the associated DNA mutation provides the great advantage of\u00a0<strong>being able to predict<\/strong>\u00a0the evolution of the tumor in the affected subject and\u00a0<strong>to eliminate or reduce the risk<\/strong>\u00a0of cancer in relatives who are carriers of the mutation.<\/p><p>Gene alterations that may predispose to tumor development have been identified for some cancers\u00a0<strong>(breast, colon, stomach, kidney, melanoma, thyroid, pancreas, parathyroid and adrenal gland)<\/strong>\u00a0and many studies are underway for other types of cancer.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Homepage For each cancer type, between 5 and 10% of cases are attributable to a hereditary form. A tumor is called hereditary when its onset is due to a genetic mutation\u00a0transmitted by the parents. Mutations in parents have a 50% chance of being passed on to their children. The latter do not inherit the tumor [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":21399,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"plain-container","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ep_exclude_from_search":false,"footnotes":""},"page-tags":[],"sezione-pagina":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.4 - 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