For each cancer type, between 5 and 10% of cases are attributable to a hereditary form. A tumor is called hereditary when its onset is due to a genetic mutation transmitted by the parents.
Mutations in parents have a 50% chance of being passed on to their children. The latter do not inherit the tumor itself, only the predisposition to develop that tumor more easily than the general population.
Individuals carrying a genetic mutation predisposing to a specific cancer are considered to be at high risk and must undergo appropriate prevention protocols.
Identifying and treating tumors with a familial origin is a challenge that requires special resources and skills. This is why IOV created the Hereditary Tumors Unit, which works in synergy with the Unit of Immunology and Molecular Diagnostics, specializing in the following neoplasms:
- familial colorectal cancer
- hereditary endocrine / neuroendocrine tumors
- hereditary breast and ovary cancer
- familial melanoma
- hereditary kidney cancer